The BU ACUC shall evaluate and approve all protocols of proposed scientific procedures involving the use and manipulation of laboratory animals. These refers to any live vertebrate animal, whether in a domestic or wild state. This may also include activities that entails manipulations of animals such as researches, experiments, studies or investigations, teaching and instructions and product testing (food, drugs, agrochemicals and cosmetic testing). The review is specifically on animal care and use, not a review or evaluation of the entire merit of the study. The BU ACUC shall monitor and review the implementation of the approved scientific procedures through the conduct of facility inspections. Also, institutions shall periodically review written procedures to ensure consistent application of standard principles pertaining to the humane care and use of laboratory animals.